| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdb44e1fc3713b00d09f22135dee0510 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-79 |
| filingDate |
2014-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32fc5a548920f372b0d0c3dbf08aeea6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5be337983bfc50c1a314316715a5bc9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc9a5828ba6a052f07354aae2bddea4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1450b432270ce46e48788476e565ee22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dabfad6c292b34f8bf12ef31de2bece
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ca3e83fca7c88654d9e4df7933e147a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f80a7b9803dfb221956cd8ce751f10b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebf04e870183250ceacae2fe81c393bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5f16881b440eac5687ec8849e2de34d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a869ef1971e64b796a599734caae9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e147670e16f7949d50e3608d66e757b |
| publicationDate |
2017-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017218038-A1 |
| titleOfInvention |
Pharmaceutical compositions containing, as active ingredient, granulocytecolony stimulating factor mutant protein or transferrin fusion protein thereof |
| abstract |
The present invention relates to a fusion protein in which transferrin is peptide-bonded to a terminal of a granulocyte-colony stimulating factor (G-CSF) protein or a G-CSF mutant protein in which the 116 th threonine is substituted with cysteine in the amino acid sequence of the G-CSF. Specifically, the granulocyte-colony stimulating factor (G-CSF) mutant protein of the present invention or the transferrin fusion protein thereof displays a significantly increased specific activity and blood stability, compared with the conventional human G-CSF, and has a higher purification efficiency than the conventional PEGylated G-CSF characterized by the extended half-life, so that it can be advantageously used for preventing or treating ischemic diseases or neutropenia. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019067532-A1 |
| priorityDate |
2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |