Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16f82fbf42b4420bfabe6f79f929c458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e5bb9802ba5fdfa468a8b25cdf4a53b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155 |
filingDate |
2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57c88633d40a9adc6d122996d405160a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8576d274f54dd685698df9f006c9859b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3824b529e134b1ae501ade8ea08f3a06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9f2fef51e63d0b03b568c900802cd0 |
publicationDate |
2017-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017189520-A1 |
titleOfInvention |
Genetically stable live attenuated respiratory syncytial virus vaccine and its production |
abstract |
Provided herein are recombinant respiratory syncytial viruses that contain mutations that make the disclosed viruses attractive vaccine candidates. The viruses disclosed contain attenuating mutations designed to have increased genetic and phenotypic stability. Desired combinations of these mutations can be made to achieve desired levels of attenation. Exemplary vaccine candidates are described. Also provided are polynucleotides capable of encoding the described viruses, as wells as methods for producing the viruses and methods of use. |
priorityDate |
2012-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |