http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017172958-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90d627fa621ae496e40488261c16712d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-255 |
| filingDate | 2015-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06d93e924c5301422f61c2fe5e2df190 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61929498e0fdc2061e119a6e86c244a6 |
| publicationDate | 2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2017172958-A1 |
| titleOfInvention | Compounds for Use in Controlling Body Fat |
| abstract | The invention relates to compounds that have utility in decreasing body fat of for preventing or decreasing the accumulation of body fat in a subject, and which inhibit the enzyme stearoyl-coenzymeA desaturase (SCD). The compounds have Formula I; where; R 1 is a C 1 to C 8 linear, branched or cyclic alkyl or alkenyl group having up to two double bonds, and optionally substituted with one or more groups selected from (i) one or more halogen atoms; (ii) alkoxy group of formula OR 6 ; (iii) hydroxy; and (iv) carboxyl group of formula COOR 7 ; R 2 , R 2 , R 3 , R 3 are independently and for each occurrence selected from (a) hydrogen; (b) C 1 to C 4 alkyl optionally substituted with one or more groups selected from (i) to (iii) above; (c) halogen; and (d) C 1 -C 2 alkoxy. Where R 2 and R 2 are both selected from either (b) or (d), R 2 and R 2 can optionally be linked. Where R 3 and R 3 are both selected from either (b) or (d), R 3 and R 3 can optionally be linked; R 4 and R 5 are each independently selected from hydrogen and C 1 to C 4 alkyl optionally substituted with one or more groups selected from (i) to (iii) above; R 6 is selected from linear, branched or cyclic C 1 to C 4 alkyl optionally substituted with one or more halogen atoms; R7 is selected from hydrogen and linear, branched or cyclic C 1 to C 4 alkyl; and x is an integer from 1 to 3. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116392486-A |
| priorityDate | 2014-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.