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publicationDate 2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2017172953-A1
titleOfInvention Self-assembling drug delivery vehicles with ionically cross-linked drugs
abstract A composition and system for delivering a therapeutic agent is provided. The composition includes a self-assembling peptide ionically cross-linked with a charged therapeutic agent. In the presence of the charged therapeutic agent, the peptide self-assembles to form a nanofibrous hydrogel scaffold, wherein the hydrogel structure is quickly recoverable following a shear stress thereby permitting administration of the composition by syringe-needle or catheter injection. Methods of using the composition is also provided.
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