| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751562df05f1831baef905641425c407 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-183 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
| filingDate |
2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e81edd7a9c30e92164b92f9908a4aa9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a214f901a21857c670db0af6454d9d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_773092adc4e27bc135e45a13dc379f7e |
| publicationDate |
2017-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017151351-A1 |
| titleOfInvention |
Gd-ENCAPSULATED CARBON DOTS AND METHODS OF MAKING AND USING THEREOF |
| abstract |
Gd-encapsulated carbonaceous dots (Gd@C-dots) hold great potential in clinical translation as Ti contrast agent for magnetic resonance imaging. However, current synthetic techniques yield particles with poor size control; hence, time-consuming size selection is often needed to obtain particles of desired sizes. Disclosed is a process whereby mesoporous silica nanoparticles are used as templates for size-controlled synthesis of Gd@C-dots. The disclosed methods involve calcining a mixture comprising a mesoporous silica nanoparticle, a gadolinium-containing compound, and a chelator, thereby forming the nanoparticles of gadolinium within the mesoporous silica nanoparticle; and removing the mesoporous silica nanoparticle from the nanoparticles of gadolinium. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110251688-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114058363-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110522928-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113549450-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109233828-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109705627-A |
| priorityDate |
2015-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |