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publicationDate 2017-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2017146543-A1
titleOfInvention Use of TM9SF4 as a biomarker for tumor associated exosomes
abstract The present invention relates to extracellular microvesicles biomarkers for determining the tumour transformation status or presence of a tumour in a subject, and to the uses of such biomarkers and to diagnostics methods using such biomarkers. In particular, the methods and uses of the invention involve isolation of TM9SF4-positive extracellular vesicles and detection of the expression of a second biomarker, preferably selected from the group consisting of CD9 protein, miR-21 and RNU6.
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