| abstract |
The present invention provides a method of separating beads in a fluidic chip comprising an internal fluid circuit through which various reactants, in which at least one of the reactants are beads, may be moved by use of centrifugal force, the method comprises the steps of: providing at least a first set of beads ( 8 a) having a density m 1 and a second set of beads ( 8 b) having a density m 2 in a section ( 7, 15, 18 ) of the fluid circuit, the section comprising at least a first outlet ( 16, 13, 17 ); providing a first liquid medium in the section, the liquid medium having a density d 3, such that m 1 <d 3 <m 2; and applying a first centrifugal force (G) such that the first set of beads ( 8 a) and the second set of beads ( 8 b) migrates in opposite directions within the section. |