http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017137894-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1432597c4e83d4ec79685539afb3f1d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2017-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e1e5318a509d1d1a7637ce9ed65bdc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f629500d64af3824636294aa3c8cca0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e0557d3d821e4059dda3f2bfff56785 |
| publicationDate | 2017-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2017137894-A1 |
| titleOfInvention | Oligonucleotides and Methods for Detecting KRAS and PIK3CA Mutations |
| abstract | Provided are oligonucleotides that are capable of detecting KRAS and PIK3CA mutations in both cancer patients and healthy individuals with high specificity in kPCR assays. When the oligonucleotides are used as forward primers in conjunction with a defined genotyping algorithm spreadsheet, the primers are capable of enhancing detection of KRAS codon 12, 13, and 61 and PIK3CA codon 542, 545, and 1047 single nucleotide polymorphisms (SNPs) in a background of wild-type sequences. The oligonucleotides of the present invention are also capable of preventing pseudogene amplification when the oligonucleotides are hybridized as reverse primers or detection probes to the mismatch sequences. |
| priorityDate | 2010-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.