| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2016-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_700985fe6ce7b9cec8ee470c48478124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e04b2195e10bcfa90ce0b80963de5c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d7baa176bc707282c12b8c30d88d9a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c3e88d4142f32da8cae36722042f31 |
| publicationDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017128477-A1 |
| titleOfInvention |
Composition for inhibiting myeloid-derived suppressor cells comprising decitabine or its pharmaceutically acceptable salt as active ingredient |
| abstract |
The present invention relates to a method for inhibiting myeloid-derived suppressor cells or treating cancer comprising administering a pharmaceutical composition containing decitabine or its pharmaceutically acceptable salt as an active ingredient. The decitabine suppresses creation of a cell population of myeloid-derived suppressor cells (MDSC) created in spleen and bone marrow in tumorigenic mice and induces apoptosis of the MDSC cell population. Therefore, the decitabine may be useful as agents for treating MDSC-related diseases and anticancer immunotherapy, or an anticancer supplement. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130812-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108254301-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786604-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11220552-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10780180-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11053240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046781-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113613641-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11702476-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107217035-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633494-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633495-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020139618-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11517567-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11136397-B2 |
| priorityDate |
2015-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |