Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23a4e0c875bf1ac2b8a3b76517de6c7d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3276 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-701 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
filingDate |
2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_700a6528170ccbf8c903bd330abc0a9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5995292def11a1a54cdfc36d4042eb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46b0255501239d693485224b93cbd002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df7fdc6df828bae3cd1816e4a39a5774 |
publicationDate |
2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017107565-A1 |
titleOfInvention |
Functionalized particles for label-free dna impedimetric biosensor for dna and rna sensing |
abstract |
In one embodiment, 3-Aminopropyltriethoxysilane (APTES) functionalized graphene oxide (APTES-GO) wrapped SiO 2 particle composite (SiO 2 @APTES-GO) was prepared via the self-assembly process of APTES-GO sheets and SiO 2 particles. Transmission electron microscopy (TEM) and Attenuated Total Reflectance-Fourier Transform Infrared spectroscopy (ATR-FTIR) confirmed wrapping of the SiO 2 particles by the APTES-GO sheets. A biosensor based on electrochemical impedance spectroscopy (EIS) was constructed and used to sensitively detect dengue DNA and dengue RNA via primer hybridization using different oligonucleotide sequences. The results demonstrated that the SiO 2 @APTES-GO electrode material led to enhanced sensitivity, selectivity and detection limit, compared to both APTES-GO and APTES-SiO 2 . The three-dimensional structure, high surface area, electrical properties and the ability for rapid hybridization offered by the SiO 2 @APTES-GO rendered this electrode material as ideal to use in the reported dengue impedimetric sensor. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10012645-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112745987-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018059099-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107475454-A |
priorityDate |
2015-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |