| abstract |
Disclosed is a compound which is useful as an AMPK activator. A compound represented by formula: n n n n n n n n n n or a pharmaceutically acceptable salt thereof,n nwherein R 4 is hydrogen, or substituted or unsubstituted alkyl,n nR 1 , R 2 and R 3 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl or the like, with the proviso that R 1 , R 2 and R 3 are not simultaneously hydrogen,n nX is a single bond, —S—, —O—, —NR 5 —, —C(═O)— or the like,n nR 5 is hydrogen, or substituted or unsubstituted alkyl,n nY is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocyclyl or the like. |