| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b81a5eda0046acaa7b584105a93cd52 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01cf2bee47e3e6c4e84f8b08fc386cac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2ad86f832be3477a9264aea63cdccb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3be22764960e5d5d5109c20f9775518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1ab6f94fb73a6e14e0220571c465a71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9f987fbf2ab1098bcef824e41a34d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d27dbe4d959a7f95fe69b270fbd9b50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_643dc45460ab0c01c872519ac20bbdaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d671c76746b17980da9e4aaf45df438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c335f6d9d31378fc0c6dc77205ab2822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cc6e43d1b55307ecca3d5a0e373d75a |
| publicationDate |
2017-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017096665-A1 |
| titleOfInvention |
Compositions and Methods for Inhibiting Gene Expression of LPA |
| abstract |
RNA interference (RNAi) agents and RNAi agent conjugates for inhibiting the expression of the LPA (apo(a)) gene are described. Pharmaceutical compositions comprising one or more LPA RNAi agents optionally with one or more additional therapeutics are also described. Delivery of the described LPA RNAi agents to liver cells in vivo provides for inhibition of LPA gene expression and treatment of cardiovascular and cardiovascular-related diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019211333-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10995335-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022121959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111107853-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113227372-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020533334-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019078089-A1 |
| priorityDate |
2015-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |