| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2471a24501b6ff9c0832f9fdbc1b73d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2015-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f620ab504406c556be2c3f1524a4600c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1808e779e4daf3e05cd9fddd41809d6d |
| publicationDate |
2017-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2017096457-A1 |
| titleOfInvention |
Anti-inflammatory compounds and methods of use |
| abstract |
Disclosed herein are methods of treating or inhibiting inflammation in a subject by administering an anti-inflammatory protein to the subject. In some embodiments, the protein has at least 80% sequence identity to the amino acid sequence set forth as SEQ ID NO: 1 or fragments thereof. Also disclosed are methods of identifying anti-inflammatory compounds by determining the effect of test compounds on inflammation in zebrafish gut. In some embodiments, germ-free zebrafish or zebrafish inoculated with a single defined bacterial strain are contacted with one or more test compounds and a marker of inflammation in the gut is measured and compared to a control. Recombinant vectors including a nucleic acid encoding the anti-inflammatory protein (such as a nucleic acid encoding a protein with at least 80% sequence identity to SEQ ID NO: 1 or fragments thereof) operably linked to a heterologous promoter are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208445-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019152418-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10752662-B2 |
| priorityDate |
2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |