http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017073758-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_558514e7c79e7c262491474fff0ba6b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e3273aa2c3ac38bedcaa0d7bb663df0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e166bbc8526aad55784e8370b5818f60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1365fff23a61933b8fdf1666ee3a4a20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e69e255af0dc38fd0670c94284c7d151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fbaf93ba115751a32c14509c1060180 |
publicationDate | 2017-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2017073758-A1 |
titleOfInvention | Methods and materials for identifying the origin of a carcinoma of unknown primary origin |
abstract | The present invention provides a method of identifying origin of a metastasis of unknown origin by obtaining a sample containing metastatic cells; measuring Biomarkers associated with at least two different carcinomas; combining the data from the Biomarkers into a linear discrimination analysis where the linear discrimination analysis normalizes the Biomarkers against a reference; and imposes a cut-off which optimizes sensitivity and specificity of each Biomarker, weights the prevalence of the carcinomas and selects a tissue of origin determining origin based on highest probability determined by the linear discrimination analysis or determining that the carcinoma is not derived from a particular set of carcinomas; and optionally measuring Biomarkers specific for one or more additional different carcinoma, and repeating the steps for additional Biomarkers. |
priorityDate | 2007-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1034.