Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36333273e27f0db23ddddbf80ba79ba7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H10K10-462 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H10K85-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4145 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-414 |
filingDate |
2016-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b0eb3c7eceae6836d47c40a116768a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_791354b7f052e82cb8f20ce2257165ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fbd1a95bf10cbc8f3225757122e756c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_915827967ebfbbedc9d556f8e7a8f367 |
publicationDate |
2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017067890-A1 |
titleOfInvention |
On-Chip Disease Diagnostic Platform for Dual-Gate Ion Sensitive Field Effect Transistor |
abstract |
Dual-gate ion-sensitive field effect transistor (ISFET) and methods implementing the dual-gate ISFETs for disease diagnostics are disclosed herein. An exemplary method includes providing a biological sample to a dual-gate ISFET. The dual-gate ISFET includes a fluidic gate structure and a gate structure, where the fluidic gate structure and the gate structure are disposed over opposite surfaces of a device substrate. The method further includes generating enzymatic reactions from enzyme-modified detection mechanisms. The enzyme-modified detection mechanisms release ions into an electrolyte solution of the fluidic gate structure. The method further includes biasing the fluidic gate structure and the gate structure to generate an electrical signal as a sensing layer of the fluidic gate structure reacts with the ions. The electrical signal indicates an ion concentration in the electrolyte solution that correlates with a presence or a quantity of target analytes in the biological sample. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017184541-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10466199-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102017123949-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11243184-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021239688-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017110678-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10043990-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10533966-B2 |
priorityDate |
2011-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |