Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b758fecaba243429625442aa212e8701 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-24 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-26 |
filingDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43ba09dcae023d7ffcde716d46833856 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ba45415d76329c3e348fe660de4e5c2 |
publicationDate |
2017-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017044107-A1 |
titleOfInvention |
Inhibitors of JMJD2C as Anticancer Agents |
abstract |
The present disclosure provides compounds, pharmaceutical compositions and related methods for the treatment of cancer, e.g., castration-resistant prostate cancer (CRPC). Specifically, the present disclosure provides a series of 8-hydroxyquinoline derivatives which show cytotoxic effects on androgen-independent prostate cancer cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019100769-A1 |
priorityDate |
2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |