Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48692 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
filingDate |
2016-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77eb3e77b08770ee72498fd7f64d78c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cfca8ab029605f6fc5856ae683f287e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f5b869ac50129c7af8928e6b900a15d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c23f1e3a37d6f72bea37e85f56074614 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9472d60777f14645494848adfd83fded http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89ee951ff6299f9230f93d86163837bd |
publicationDate |
2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017020991-A1 |
titleOfInvention |
Insulin conjugate using an immunoglobulin fragment |
abstract |
An insulin conjugate having improved in vivo duration and stability is provided. The conjugate is prepared by covalently linking insulin with an immunoglobulin Fc region via a non-peptidyl polymer, a long-acting formulation comprising the same, and a preparation method thereof. The insulin conjugate of the present invention maintains in vivo activity of the peptide at a relatively high level and remarkably increases the serum half-life thereof, thereby greatly improving drug compliance upon insulin treatment. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110545849-A |
priorityDate |
2010-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |