| abstract |
In one aspect, the invention relates to compounds having the formula: n n n n n n n n n n where R 1 , R 2 , R 3 , R 4 , and R 5 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds. |