http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017002385-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de4985aed692e75549ab8aba070d7924
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_180eb84bace6fb2cc9dd6d187b7fbe10
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-625
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
filingDate 2016-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef03dd997954a69d8ce658da4ddb7287
publicationDate 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2017002385-A1
titleOfInvention Using cell debris generated from pha recovery for enhanced cell growth and biopolyester formation
abstract The present invention relates to a process for producing biodegradable polymeric materials including polyhydroxyalkanoates (PHAs) by using the cell debris left from PHA recovery and purification. The process comprises: (a) cultivating PHA-producing microbial cells in a medium solution containing an organic carbon source to form PHAs that are accumulated in the cells as inclusion bodies; (b) harvesting the cells from the spent medium and solubilizing the non-PHA cell mass to obtain a PHA solid and a cell debris solution; (c) separating the PHA solid from the cell debris solution; (d) feeding the cell debris solution to the cultivation step (a). By reusing the cell debris generated from PHA recovery, the invention avoids disposal of a large amount of aqueous waste. In addition, a remarkable increase of cell growth and PHA synthesis is achieved, because the cell debris can be readily assimilated by the microbial cells as the nutrients.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11549129-B2
priorityDate 2009-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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