Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3c2e77f8dfda692ca527454d23ecc03 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 |
filingDate |
2016-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c02af6e52e3587d4297af28c32fe6df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1c0dac088a714c94834eb8c3dcdb405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c3ab733fd9bda6e844f3788c40ae42e |
publicationDate |
2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017002058-A1 |
titleOfInvention |
Compositions and methods that involve protein scaffolds that specifically bind to hepatocyte growth factor receptor |
abstract |
This disclosure describes a non-naturally occurring protein scaffold that specifically binds to hepatocyte growth factor receptor (MET) and methods of using such protein scaffolds. Generally, the protein scaffold includes a frame and at least one loop region that specifically binds hepatocyte growth factor receptor (MET). The frame generally includes a plurality of structural domains that include at least one β structure or at least one a helix. The loop region generally includes an amino acid sequence that varies from a naturally-occurring loop region by at least one amino acid deletion, amino acid substitution, or amino acid addition. |
priorityDate |
2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |