Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cea139ad438b9ce7d33159d45b154c6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60165f3403b3b7f379f262fe11bd3909 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2016-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5b9ee79a14fcfa46b250b7d52c36f66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17742acb654b652d03aadf81e751c841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc820bea05bd7b81224ceac1e72ce6d |
publicationDate |
2016-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016361396-A1 |
titleOfInvention |
Aquaporin 2 protects cattle from ticks and tick-borne parasites |
abstract |
A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2023127041-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11771746-B2 |
priorityDate |
2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |