http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016349155-A1

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filingDate 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f8510eb8a7cf0ae557ed449d5672ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3859ec1b328a4337868e1e2d314b86c9
publicationDate 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016349155-A1
titleOfInvention Nerve culture system
abstract Techniques and systems are disclosed for a bioassay that is an in vitro mimic of peripheral nerve generation using the sensory neurons that innervate the peripheral nervous system. In some embodiments, the techniques may assist in detecting the bioactivity or potency of nerve grafts (e.g., processed, acellular human allografts) for fostering or supporting peripheral nerve regeneration. In various embodiments, techniques comprise affixing neurons (e.g., a DRG) to a nerve graft segment to form a test construct; culturing the test construct in a medium; analyzing the test construct to indicate the amount of outgrowing nerve structure; and determining the potency of the nerve graft from a metric derived from the analysis. In some embodiments, techniques and materials may be used to test the effect of a varied test condition on nerve growth.
priorityDate 2015-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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