| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2015-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0389d0c00e96e445e85774ca17045f1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0461697e07eed23f47e7cb6c85596662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be839f7f3cdbe6f18862115ff4ce891f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_252eb63d00b9932709a6723cb83179ed |
| publicationDate |
2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016341729-A1 |
| titleOfInvention |
Biomarkers for detecting and monitoring colon cancer |
| abstract |
A metabolic profiling approach for identifying biomarkers that provide highly sensitive and specific colorectal cancer (CRC) detection and monitoring using serum samples. The methods can be used for distinguishing CRC patients from both healthy controls and polyp patients, as well as to monitor disease progression or response to therapy. Receiver operator characteristic curves generated based on these models showed high sensitivities for differentiating CRC patients from healthy controls or polyp patients, good specificities, low false discovery rates, and excellent areas under the curve were obtained. Monte Carlo cross validation (MCCV) was also applied, demonstrating the robust diagnostic power of this metabolic profiling approach. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020408762-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019173631-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109580948-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114755422-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114910579-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109884300-A |
| priorityDate |
2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |