http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016320377-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cded1dd9dcc9dac6c1d9e44d8c1f78f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-79 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54333 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2015-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_262e31462bae218cde5a8e947052c8be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_315b4afa504dec21feda4eb2b4e123ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdbe5c16ebda605fb5776a8a62e64125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e4dde1595953097cb2274eac17be225 |
| publicationDate | 2016-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2016320377-A1 |
| titleOfInvention | Method for protein analysis |
| abstract | The present invention relates to a method for protein analysis in which the proteins to be analyzed are displayed on a population of discrete and dispersible structures, such as beads or other particles, for subsequent affinity reactions and analysis/detection. More closely the invention relates to a method for protein analysis comprising providing a denatured protein sample in the presence of a denaturing agent, the method comprising the following steps; n a) contacting said protein sample with a population of discrete and dispersible protein-binding structures to capture a plurality of different proteins on said structures,n nb) removal of denaturing agent to display protein- and protein-feature specific epitopes from said sample on said structures;n nc) performing affinity probing targeted to a sub-group of said protein or protein feature specific epitopes requiring two or more specificity building events per targeted protein or protein feature generating a target specific nucleic acid molecule or sequence for each of the targeted proteins or protein-features;n nd) liberating said protein- or protein-feature specific nucleic acid sequences or their complements from said structures;n ne) optionally amplifying said nucleic acid sequences;n nf) analysing the generated nucleic acid molecules by a quantitative and sequence specific nucleic acid detection method; andn ng) determining therefrom the quantity or presence of targeted proteins or protein features in said sample. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113390837-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115494243-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106754894-A |
| priorityDate | 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.