| abstract |
The present invention is based on the surprising discovery that the overexpression of the SCL gene, of nucleotide sequence SEQ ID NO: 1, increases the production of megakaryocytes and platelets from stem cells. Likewise, it has been proven that this increase also occurs using PSCs which, unlike CD34+ HSC cells which have a limited expansion capacity, are characterized by an unlimited growth capacity, and can result in the unlimited production of platelets for the use thereof in clinics. |