| abstract |
Provided herein are apparatuses and methods using a compact scanner assembly for multi region of interest (MROI) imaging and targeting of an intact tissue sample. The compact scanner assembly for MROI imaging, comprises a set of three electromagnetically actuated scanning mirrors, the first comprising a resonant scanner (R) driven at its resonant frequency, the second comprising a galvanometer scanner (G 1 ) having a mirror (m 1 ), the third comprising a galvanometer scanner (G 2 ) having a mirror (m 2 ), wherein the galvanometer scanners (G 1 ) and (G 2 ) are driven by a lower bandwidth control signal specifying an angle for mirror (m 1 ) and (m 2 ), wherein the scanners are arranged sequentially as (R) (G 1 ) (G 2 ), wherein the set of three scanning mirrors are within a single scanner assembly (RGG), wherein the compact scanner assembly for MROI combines raster scanning with random-access scanning to target multiple ROIs for targeting and imaging. |