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publicationDate 2016-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016299136-A1
titleOfInvention Aptamer-gated nanoparticles for lateral flow assays
abstract The invention relates to a method for performing single step assays for the determination of the presence or absence of an analyte in a liquid sample, on a solid surface. The method disclosed, comprise an aptamer coated and signal molecule loaded porous silica particles immobilized on a porous solid material. Specific interaction of the analyte with the aptamers coated on the silica beads, cause release of the signal molecules which result in a detectable signal on the solid support. Also provided are assay devices for the detection platform.
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