| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_065fe7c4146d471ac47823ff7c1d911f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate |
2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4042123fb012d38d20e144a193c5470b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46bf3f0131a86576e1a2f8f63b04623f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9ac9253a85720a6718037c793da4365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b31506eb35de54f36992fb478c1d285d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9714b00c43b2a5ecdd33320d9622e4d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba3c4ccf23e4f29d166810f22ed071d |
| publicationDate |
2016-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016289206-A1 |
| titleOfInvention |
Carboxymethyl piperidine derivative |
| abstract |
The present invention provides a new compound which has NK 1 receptor antagonist activity, whose CYP3A4 inhibitory activity is reduced compared to aprepitant, and which are useful for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting. That is, the present invention relates to carboxymethyl piperidine derivatives represented by the following formula (I) or a pharmaceutically acceptable salt thereof. Wherein, ring A is a benzene ring or the like; ring B is a pyridine ring or the like; R 1 is C 1-6 alkyl or C 1-6 alkoxy; R 2 and R 3 are a hydrogen atom or methyl; and n is an integral number from 0 to 5. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10399949-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10011568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708266-B2 |
| priorityDate |
2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |