http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016282367-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_125f8fe15735ac26132299b5dd425405 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-775 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 |
filingDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ee67a3e0dd7fb8c31a13c4819c5353a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7232df813de3481df3c43d35b7946a07 |
publicationDate | 2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2016282367-A1 |
titleOfInvention | Methods for calibrated ion mobility analysis and uses thereof |
abstract | The present invention relates to improved ion mobility analysis (IMA) methods that can accurately quantify particle concentration in a sample solution. Specifically, reference particles of known solution-phase concentration are used for calibration. In addition, by exploiting spectral deconvolution techniques, the concentrations of subpopulations within the particles can also be accurately quantified. The improved IMA methods permit, for the first time, the quantification of absolute concentrations of HDL particles and subpopulations thereof in a biological sample. The correlations of HDL particle concentrations and conditions such as LCAT deficiency and cardiovascular diseases have been established. Accordingly, the present invention also provide methods to determine whether a subject is at risk to develop or is suffering from these conditions by using HDL particle concentration as a clinical metric. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110361307-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115773977-A |
priorityDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 455.