Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44e0905262f429c7590b40df8448c0c5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 |
filingDate |
2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_302c8078ed144124091ba3e19b983a32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02dc32ddb4afc4be7e16c05968f969b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5ee2f4855ed69d7dc7ecf11ca0e478c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e49662110424e8018fc05f1a30ee0d99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_161c16c21ad195d38cd7d68f7858f036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6325ba577694d72a17e60a1836bf9a67 |
publicationDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016279078-A1 |
titleOfInvention |
Stable Formulation for Parenteral Administration of Tapentadol |
abstract |
The invention relates to an aqueous pharmaceutical composition for parenteral administration comprising Tapentadol or a physiologically acceptable salt thereof, wherein the concentration of Tapentadol is within the range of from 0.10 to 8.00 mg/mL, based on the weight of Tapentadol free base and based on the total volume of the composition; and wherein the pH value of the composition is buffered and within the range of from 4.0 to 6.0. The invention also relates to a container comprising the pharmaceutical composition and a process for the preparation thereof. The invention also relates to a kit comprising the contained according to the invention in a packaging. The pharmaceutical composition according to the invention is particularly useful for treating pain, especially acute pain, preferably in pediatric patients. |
priorityDate |
2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |