| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71216bbae7251600ab05113c528ee3cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2201-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L89-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8780d50add46e3bf56e2cdcf89e7b50f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c2987227c1c79942167db4a56b866c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04686d1cfee143d7ce1d1f9ecb7598f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97475e756c554f0245e32b274a224793
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc5ccf8250e1ce6ed7345ddf599f60bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95f995982b88cd253f3219d8954b67f6 |
| publicationDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016266143-A1 |
| titleOfInvention |
Biocompatible and Bioabsorbable Derivatized Chitosan Compositions |
| abstract |
The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229724-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10709817-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925310-B2 |
| priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |