Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bce66e7f2d4c091955949fd81a3d9cf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 |
filingDate |
2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31de817c50deb56244b2391db3634bbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0389a66813c62a0feb7ff33960ef5daf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e8ef4b84167ab8f685414d3e1dac0c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f05c59a98ef54622c94104a664b69ccd |
publicationDate |
2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016264999-A1 |
titleOfInvention |
Engineering neural stem cells using homologous recombination |
abstract |
Described herein are recombinant polynucleotide-binding polypeptides, recombinant fusion proteins made with the described polynucleotide-binding polypeptides, methods of using the described recombinant polynucleotide-binding polypeptides and recombinant fusion proteins to modify genomic DNA of cells and, in some embodiments, create recombinant cells. Methods are also provided herein for genetically modifying a neuronal stem cell. Methods are also provided for treating a neurological disorder in a subject that include the administration of genetically modified neuronal stem cells produced by the methods disclosed herein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11331346-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033584-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020006131-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083753-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11590171-B2 |
priorityDate |
2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |