| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a412a5d1b2dbe3cee616dbc52e1489 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2318-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-64 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2016-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0be779514818afac51f783739661a17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49db7314e24000f03f876ccaff489f2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da3910a67b3c97a1fe2c7c93d10a6cef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a30fca7a4e50c04b3a54fe84f17af17d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ddf54865e77fff4e38b301ddb5fa936
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bffdb5f4f48ac49607ebd728954468e |
| publicationDate |
2016-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016257763-A1 |
| titleOfInvention |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain |
| abstract |
Provided herein are isolated heteromultimers comprising: at least one single domain antigen-binding construct attached to at least one monomer of a heterodimer Fc region; wherein the heterodimer Fc region comprises a variant CH3 domain comprising amino acid mutations that promote the formation of said heterodimer with stability comparable to that of a native Fc homodimer; and wherein said isolated heteromultimer is devoid of immunoglobulin light chains and optionally devoid of immunoglobulin CH1 region. These novel molecules comprise complexes of heterogeneous components designed to alter the natural way antibodies behave and that find use in therapeutics. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11168149-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10077298-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9988460-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172571-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10875931-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9732155-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457742-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019035938-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11604196-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172605-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172601-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-202019005887-U1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018222901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9771573-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020172598-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021217085-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11306156-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10955420-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10690676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018362668-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019055631-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11161915-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021138407-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019178364-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019178362-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10753945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10947295-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020010250-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11209439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021092355-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018151820-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10508154-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017165464-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9574010-B2 |
| priorityDate |
2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |