| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e757fd4fedc4fe825bb81b1b466a0947
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1809 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-0241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-183
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L69-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L69-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2015-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_977e0f1a6bacc65159ea1a867f3624c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_532cfb2350edbc161564ad83dc3d4188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e198aa8ef1f5bf8a50c6f58d63d0d53c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb356ae7571a3d11f5c7d775777405f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e914d4c2fd24e1a3d0856b49bda0f73 |
| publicationDate |
2016-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016220705-A1 |
| titleOfInvention |
Biodegradable organic radical-functionalized polycarbonates for medical applications |
| abstract |
Paramagnetic, amphiphilic, biocompatible polymers were prepared comprising a carbonate repeat unit bearing a paramagnetic organic radical, more specifically a nitroxyl radical. The radical polymers can be produced in one step from a precursor polymer bearing an active ester side chain by treating the precursor polymer with a radical-bearing nucleophile. The precursor polymer can be prepared by organocatalyzed catalyzed ring opening polymerization (ROP) of a cyclic carbonate monomer bearing an active ester side chain. The radical polymers can be non-toxic and partially biodegradable. The radical polymers have utility as contrast enhancing agents in a medical imaging application and/or as therapeutic agents for treating a medical condition. The radical polymers can also serve as carriers for therapeutic agents (e.g., drugs) and/or medical image enhancing agents (e.g., NIRF dyes). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463746-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11116844-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109593145-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109593145-B |
| priorityDate |
2015-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |