Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d4be1122ac19a1f6b4b45a73b1645f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2325-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2327-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2489-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L17-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate |
2014-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_419bc6427da1e4adb7c5504c219b6af1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504522a40838f32c349c414ce0454b70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57ae1ec512c94de6c6a5d187ed700208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d222c869c896e8f147eea5e512f237db |
publicationDate |
2016-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016215111-A1 |
titleOfInvention |
Materials and methods |
abstract |
The invention relates to methods of controlling orientation of direct covalent binding of a peptide to a polymer substrate surface, to surfaces with peptides directly covalently bound thereto in a manner where the orientation of binding is controlled as well as to devices comprising such substrates. In particular the invention relates to A method of controlling predominant orientation of direct covalent binding of one or more peptides to a polymer substrate surface comprising: (a) exposing the surface to energetic ion treatment to generate a plurality of activated sites comprising reactive radical species; (b) incubating the surface with one or more peptide/s that exhibit or can be induced to exhibit a dipole moment and manipulating the electric field environment and/or charge of said surface and/or of said peptide/s during said incubating; wherein predominant orientation of direct covalent binding of said peptide/s to said surface is thereby controlled. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017121479-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4136974-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11049697-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934408-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023021221-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11756772-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020388468-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11545343-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016310928-A1 |
priorityDate |
2013-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |