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publicationDate 2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016209394-A1
titleOfInvention Nanofluidic channels with gradual depth change for reducing entropic barrier of biopolymers
abstract A device for passing a biopolymer molecule includes a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel. The surface relief structure includes a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer.
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