| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86fe3583726c51c35ab26c16a118bf85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f1f8f8635438ba45ef1b082d4afd2cc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B29-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B7-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B29-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C30B7-14 |
| filingDate |
2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c118fc8464b3af60be86c8211e4356b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75b269fd3e5976c8375b521392788700
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_045a0fba650f0dc0e6077a3badbbe17e |
| publicationDate |
2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016207911-A1 |
| titleOfInvention |
Crystal Form of Dabrafenib and Preparation Method and Use Thereof |
| abstract |
The invention relates to a new crystal form of dabrafenib and preparation method thereof. With respect to known crystal forms, the new crystal form has the advantage of being more stable at room temperature or in aqueous systems, and has low hygroscopicity, and thus is more suitable for a wet granulation process or being prepared into a suspension. The present invention also relates to a pharmaceutical composition and formulations comprising the new crystal form, and their use in the treatment of Raf family kinase-related diseases. |
| priorityDate |
2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |