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filingDate 2014-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2016-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016194605-A1
titleOfInvention Design and use of specific regulatory t-cells to induce immune tolerance
abstract The present invention generally relates to the production of antigen-specific T regulatory cells (Tregs). Such cells can be used in therapy to minimize undesirable immune responses such as those observed in autoimmunity and hemophilia and other diseases as well as in the response to protein therapy for genetic diseases. Methods for producing antigen specific Tregs and conditions for preferential expansion of functionally stable, specific Tregs are also provided.
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