http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016178622-A1

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filingDate 2015-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a4c8250c81d9a1c56534f803e74c687
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publicationDate 2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016178622-A1
titleOfInvention Aptamer-Based Biosensing
abstract The present disclosure relates to a biosensor device for detecting a predetermined target analyte. The device comprises a substrate. An aptamer bioreceptor for specifically binding to the predetermined target analyte is exposed at a functionalized surface of the substrate. The device also comprises a heat source for heating the substrate via a back surface thereof. The device further comprises a first temperature sensing element for sensing a temperature at the back side of the substrate and a second temperature sensing element for sensing a temperature at the functionalized side of the substrate. The device also comprises a signal processing unit for calculating a heat transfer resistivity value based on temperature values obtained from the first and the second temperature sensing element and the heating power generated by the heat source.
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priorityDate 2014-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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