Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbdc68ca0aa38fef2d059853ef2b31e6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48176 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-145 |
filingDate |
2015-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d8005f9f3f501eedbe6ce8730c96896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a83b4e842b1514b96b3e1fddc30ece9 |
publicationDate |
2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016166706-A1 |
titleOfInvention |
Polymeric Prodrug of Disulfiram and Application Thereof |
abstract |
Polymer/drug conjugates that can selectively target and kill cancer cells are described. Conjugates can include a copolymer formed by the reaction of a biocompatible hydrophilic component and a disulfiram derivative. The copolymer reaction product can include additional functional groups pendant to the backbone via a disulfide linkage, for instance copper chelators. The hydrophilic component can form the polymer backbone and/or can form hydrophilic pendant groups off of the backbone. Copper ions can be associated with the copolymer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019126054-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113683541-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11045553-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11007273-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108543077-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019010231-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107519497-A |
priorityDate |
2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |