abstract |
Methods for preventing or treating retroviral infection not HIV and/or for preventing, inhibiting or treating a disease caused by the retroviral infection include contacting a cell with compound (I) n n n n n n n n n n n n wherein: n n n n n n n n n n n n n n means a pyridazine, pyrimidine or pyrazine group, R independently represent a hydrogen atom, halogen atom or group chosen among a —CN, hydroxyl, —COOR 1 , (C 1 -C 3 )fluoroalkyl, (C 1 -C 3 )fluoroalkoxy, —NO 2 , —NR 1 R 2 , (C 1 -C 4 )alkoxy, phenoxy and (C 1 -C 3 )alkyl group, the alkyl being optionally mono-substituted by hydroxyl group, n is 1, 2 or 3, n′ is 1 or 2, R′ is a hydrogen atom, halogen atom or group chosen among (C 1 -C 3 )alkyl group, hydroxyl group, —COOR 1 group, —NO 2 group, —NR 1 R 2 group, morpholinyl or morpholino group, N-methylpiperazinyl group, (C 1 -C 3 )fluoroalkyl group, (C 1 -C 4 )alkoxy group and —CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C. |