http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016121017-A1

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filingDate 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c804d8f42c80c1b09abfdc322b30f2e
publicationDate 2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2016121017-A1
titleOfInvention SINGLE SOLUTION of Gel-LIKE FIBRIN HEMOSTAT
abstract The present invention trademarked ClotGel© is a fibrin II-based hemostat made of two components that are mixed into a single syringe to be delivered as an adjunct or primary treatment in moderate intraoperative hemorrhage and in trauma. It can be applied topically to the wound either on the skin in a laparatomy or as non-invasive manner in surgical procedures. Its cross-linking technology generates an adhesive stable fibrin clot required for hemostasis. The agent consists of a cross-linked gelatin that is homogenized in a solution of fibrin monomer in acetic acid, which is reconstituted before use from a lyophilized fibrin monomer. When both components are mixed into a syringe they produce a viscous gel-like composition that is polymerized and stabilized when in contact with blood. The attachment properties of the composition, as well as the rapid formation of a fibrin clot, ensures that a strong stable blood clot is formed over a bleeding wound within 2 minutes of application.
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