abstract |
The present invention comprises compounds of Formula I. n n n n n n n n n n wherein:n nR 1 , R 2 , R 3 , R 4 , R 5 , R 7 , R 8 , andn n n n n n n n n n n are defined in the specification. n The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORĪ³t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1. |