http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016115555-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94fed5c930877f1da915c6468ba0db91 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01baea3b69ec447248536676722bb719 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0a859a4dd3ad2781ba8cf4df20a3f21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08f73e670fb5ef0da41a5b0343134349 |
| publicationDate | 2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2016115555-A1 |
| titleOfInvention | Biomarkers for differentiating melanoma from benign nevus in the skin |
| abstract | Disclosed is a method for diagnosing melanoma in a human subject, as well as a method for providing a prognosis to a human subject who is at risk of developing melanoma recurrence, and a method for determining the stage of melanoma in a human subject, comprising the step of determining the level of expression of phosphatase and actin regulator 1 (PHACTR1) gene, or fragments thereof, either alone or in combination with the level of expression of secreted integrin-binding phosphoprotein (SPP1), preferentially expressed antigen in melanoma (PRAME), growth differentiation factor 15 (GDF15), and chemokine C-X-C motif ligand 10 (CXCL10) genes. Further, the invention relates to a diagnostic kit, comprising at least one substance for detection of the expression of PHACTR1, or fragments thereof, either alone or in combination with the detection of SPP1, PRAME, GDF15, and CXCL10, for the diagnosis or prognosis of melanoma. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020022895-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019199643-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788124-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4063519-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020392582-A1 |
| priorityDate | 2010-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.