| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b944100daf03103e6704d7474fd127 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0078 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a46a4a8c6f1208a86f0aa077acdc75ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_064fded12224d1dddbcf3e67fc35efe8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c09aac9c8a1d56bc908d814703d44a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e17af59e2295f156aaae63ad32e5b3e9 |
| publicationDate |
2016-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016106869-A1 |
| titleOfInvention |
Fluorescent solid lipid nanoparticles composition and preparation thereof |
| abstract |
The present invention discloses a solid lipid nanoparticle (SLN) comprising: a) a solid lipid core comprising at least a glyceride and/or at least a fatty acid; b) a mixture of amphiphilic components forming a shell around said core a); c) an alkaline-earth complex with a compound of formula I and/or II: d) at least a fluorescent dye selected from: a cyanine fluorescent dye and/or a polyetherocyclic compound selected from: coumarin, pyrano, quinoline, pyranoquinoline, indole and pyranoindole derivates in acid form or a pharmaceutically acceptable salt thereof. These nanoparticles allow a prolonged blood circulation half-life, show enhanced photostability and improved fluorescence signal. The dye is preserved from degradation and improves the fluorescent quantum yield. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019116062-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021010051-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10238756-B2 |
| priorityDate |
2013-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |