| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70517 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01B9-02015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01B11-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01B9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01B11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2014-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb675fbf06bff6af914bf9120dbeab3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_991ed5c3d5b4d87f22513f06844cf8fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15985074c2006deb12df988cde717806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd350f35e6456d106f019e6b27ca0472 |
| publicationDate |
2016-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016103118-A1 |
| titleOfInvention |
Identifying desirable t lymphocytes by change in mass responses |
| abstract |
In certain embodiments methods of identifying T cell receptors that respond to specific target cell antigens are provided, where the methods comprise providing a substrate bearing a plurality of target cells (e.g., mammalian cells); contacting the target cells on the substrate with CD8+ T cells; and using label-free optical imaging to identify an increase in mass of a T-cell and/or a decrease in mass of a target cell, where an increase in mass of a T cell and/or a decrease in mass of a target cell is an indicator that said T cell bears a T cell receptor activated by antigens presented on said target cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10203331-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018053462-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018112449-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11525153-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11480572-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10802012-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9810683-B2 |
| priorityDate |
2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |