| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_037a04de44d2ad3faffd38183dd9a2f5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-34 |
| filingDate |
2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a85cfe465177e84f788efdb575e651aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53c7fa6357ddbb84a7d702d9754e8c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52f43544e9ac2960e083efdbcbabdce3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbbb8c790188d12d40fc581dda82464e |
| publicationDate |
2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016090356-A1 |
| titleOfInvention |
Methods for preparing d-threo-methylphenidate using diazomethane, and compositions thereof |
| abstract |
Novel methods and systems for producing a substantially pure d-threo stereoisomer of methylphenidate or a salt thereof are provided. In particular, methods and systems for producing d-threo-methylphenidate hydrochloride in pure stereoisomeric form from d-threo-ritalinic acid hydrochloride using diazomethane are described. The described methods can be performed on a large scale, and thus provide d-threo methylphenidate or a salt thereof, and particularly the hydrochloride salt of d-threo-methylphenidate, in stereoisomerically pure form and in large quantities from a single batch reaction. Also described are novel compositions of d-threo methylphenidate hydrochloride. |
| priorityDate |
2014-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |