http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016089456-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0092 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 |
| filingDate | 2015-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39786d462497bad1fb74ba7bdc4d28b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0251c2d0782ab5a4ae444bcefbd4e6a7 |
| publicationDate | 2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2016089456-A1 |
| titleOfInvention | Methods devices and systems of preparing targeted microbubble shells |
| abstract | Targeted microbubbles are generated by post-labeling buried ligand microbubbles. According to embodiments, buried ligand microbubbles are created with steric brushes protecting functionalized polymer tethers. Ligands were attached to the functionalized tethers by diffusion of ligands of a small size through the steric barrier. The steric barrier was substantially capable of hindering access to the tethers by larger molecules. The embodiments disclosed include methods for creating microbubble batches that can be loaded with selected ligands, for titrating the targeting ligands thereby to reduce waste and cost, and for using resulting buried ligand molecules for medical purposes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019195463-A1 |
| priorityDate | 2010-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 117.