| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b1147c26f61e06e9aafa45d211cf098 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-805 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4973
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-342
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-97 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 |
| filingDate |
2015-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcf3c754e734eaf4022cf18f565fb53e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_433d5a12294c0a99383335b7f3177cd4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0ca0095813888c37322a6380900b41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56fec91b71b2873616803edb33eea33d |
| publicationDate |
2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016089319-A1 |
| titleOfInvention |
Actives for stimulating differentiation of keratinocytes to lighten hyperpigmented skin |
| abstract |
A method is provided for identifying a material having an efficacy for reducing color contrast between a hyperpigmented skin lesion and skin surrounding the hyperpigmented skin lesion without directly affecting melanocytes or melanogenesis. The method includes the steps of applying a composition containing a material to be tested to the hyperpigmented skin lesion; and after an interval of time, observing whether the composition has effected at least one of inhibiting proliferation of keratinocytes, stimulating differentiation of keratinocytes, and improving compressive deformation of dermal papillae, in a basal layer of epidermis in the hyperpigmented lesion of skin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019194457-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10947383-B2 |
| priorityDate |
2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |