Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bcefc58df9a9b010fba8789569389ee |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-227 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-22 |
filingDate |
2015-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cec83d67f4fa69152c5b56a6c0a5787c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56ba97cda4d11f31b2337f24653b8cf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_139d6daf90f5cbf77dbe061805251fa7 |
publicationDate |
2016-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016083789-A1 |
titleOfInvention |
Nucleic acid sequencing with nanoscale electrode pairs |
abstract |
Sequencing methods, devices, and systems are described. Arrays of nanoscale electronic elements comprising two electrodes separated by an insulating layer are used to provide sequence information about a template nucleic acid in a polymerase-template complex bound proximate to the insulating region. A sequencing reaction mixture comprising nucleotide analogs having impedance labels is introduced to the array of nanoscale electronic elements under conditions of polymerase mediated nucleic acid synthesis. The time sequence of incorporation of nucleotide analogs is determined by identifying the types of labels of the nucleotide analogs that are incorporated into the growing strand using measured impedance. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11162138-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021173681-A1 |
priorityDate |
2013-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |